Stevens-Johnson syndrome and toxic epidermal necrolysis. Clinical, etiologic and histopathologic features of Stevens-Johnson syndrome during an 8-year period at Mayo Clinic. HLA genotype and carbamazepine-induced cutaneous adverse drug reactions: A systematic review. Systemic drug reactions with skin involvement: Stevens-Johnson syndrome, toxic epidermal necrolysis, and DRESS. Stevens-Johnson syndrome and toxic epidermal necrolysis: Management, prognosis, and long-term sequelae. Stevens-Johnson syndrome and toxic epidermal necrolysis: Pathogenesis, clinical manifestations, and diagnosis. Nonimmunoglobulin e-mediated (non-IgE) drug sensitivity. Lasting skin problems may cause your hair to fall out, and your fingernails and toenails may not grow as well as they did before. When your skin grows back following Stevens-Johnson syndrome, it may have bumps and unusual coloring (dyspigmentation). The condition may lead to an emergency situation in which the lungs can't get enough oxygen into the blood (acute respiratory failure). In severe cases, it can lead to visual impairment and, rarely, blindness. The rash caused by Stevens-Johnson syndrome can lead to eye inflammation, dry eye and light sensitivity. Sepsis is a rapidly progressing, life-threatening condition that can cause shock and organ failure. Sepsis occurs when bacteria from an infection enter the bloodstream and spread throughout the body. And sores in the mouth and throat can make fluid intake difficult, resulting in dehydration. Areas where the skin has shed lose fluids. Stevens-Johnson syndrome complications include:
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